| Description | The immune system was long believed to be autonomous--unconnected to the brain; Sternberg, a neuroscientist at the National Institute of Mental Health, focuses here on research done over the last few decades that disproves this belief. She methodically details the history of this science--describing, for example, the Nobel prize-winning work of three French scientists who, in 1958, discovered the "interleukins" (molecules that signal between cells), which led to further investigations into how immune cells communicate with the brain, and discussing the seminal but controversial work of Hans Selye, who in the 1950s explored the body's response to stress. Although Sternberg leavens her account with anecdotes and historical snapshots of early medical treatment, her litany of scientific experiments (mostly performed on rats) into the body-mind connection may overwhelm readers without any scientific background. Of greater interest are her reflections on the implications of this research for maintaining health and treating disease. According to Sternberg, physical and psychological stresses--such as prolonged lack of sleep, divorce or social isolation--can make people sick by adversely affecting their immune and hormonal responses. Conversely, a strong belief in healing rituals and prayer may help make them well (via the placebo effect). All in all, Sternberg is optimistic about the idea of bridging disciplines to develop new treatments for disease. B&w illustrations. BOMC selection; author tour. (May) |
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